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Lipoprotein(a) concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of lipoprotein(a) in your blood, a type of cholesterol-like particle that includes both cholesterol and a protein called apolipoprotein(a). It’s important for assessing heart disease risk.

Quick summary

["Lipoprotein(a) helps evaluate your risk for cardiovascular problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31453-4
Short code
LASV IgM Ser-aCnc
Synonyms
LASV IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a distinct protein called apolipoprotein(a). Unlike other cholesterol types, it’s not fully broken down by the liver and can build up in blood vessels over time, increasing the risk of clots and heart disease. This test specifically measures its concentration in your bloodstream.

Why Might You Need This Test?

Doctors may order lipoprotein(a) testing if you have a family history of heart disease, stroke, or early-onset atherosclerosis. It’s also used in people with known cardiovascular conditions to guide treatment decisions, such as managing cholesterol or preventing clots.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed using a specialized immunoassay method to measure lipoprotein(a) levels accurately.

What Do Results Mean?

Higher levels of lipoprotein(a) are associated with an increased risk of heart disease and stroke. While there’s no single reference range for everyone, doctors use your results alongside other health factors to assess risk and recommend personalized care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lip(a) or Lipoprotein(a)

Frequently asked questions

Why do some people get this test even if they don’t have symptoms?
Some people are tested as part of a broader cardiovascular risk assessment, especially if they have a family history of heart disease, high cholesterol, or other risk factors. Elevated levels may help doctors plan preventive measures like lifestyle changes or medications.
How often should I get this test?
Your doctor will determine how often you need this test based on your health status, risk factors, and medical history. It’s not typically done routinely unless recommended for you.
Can lifestyle changes affect lipoprotein(a) levels?
While lifestyle factors like diet, exercise, and smoking can influence overall cholesterol levels, lipoprotein(a) levels are more resistant to changes. However, managing other risk factors (like blood pressure or diabetes) may indirectly support heart health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy