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Lipoprotein(a) [Lp(a)] Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-related protein linked to increased risk of heart disease.

Quick summary

["Lipoprotein(a) levels help assess cardiovascular risk and guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7945-9
Short code
LASV IgM Titr Ser IF
Synonyms
LASV IgM Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). Unlike regular cholesterol, Lp(a) is not easily broken down by the body, which can contribute to plaque buildup in arteries over time.

Why Might You Need This Test?

Your doctor may order this test if you have a family history of heart disease, high cholesterol, or other risk factors for cardiovascular issues. It’s also used in certain genetic testing or to monitor conditions like familial hypercholesterolemia.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis using an immunoassay method to measure Lp(a) concentration.

What Does the Result Mean?

Higher levels of Lp(a) may increase your risk of heart disease, stroke, or peripheral artery disease. Your doctor will interpret the result in the context of your overall health and other risk factors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lp(a) Level

Frequently asked questions

What causes variations in Lp(a) levels?
Lipoprotein(a) levels are generally stable over time, but they can be influenced by genetics (since it’s inherited) and certain conditions like kidney disease or pregnancy. Diet and lifestyle changes may have a minor impact, but they are less significant than genetic factors.
Do I need to prepare for this test?
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader cholesterol panel. Avoid smoking or excessive caffeine for 30 minutes before your blood draw.
Can Lp(a) levels be lowered?
While there’s no medication specifically approved to lower Lp(a) levels, some studies suggest certain medications (like PCSK9 inhibitors) may help in rare cases. Lifestyle changes, such as a heart-healthy diet and regular exercise, can support overall cardiovascular health but may not directly reduce Lp(a) levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy