Serum or Plasma Anti-Hepatitis E Virus IgG Antibody (Immunoassay)
This test measures antibodies in your blood that your immune system produces in response to Hepatitis E virus infection. It helps determine if you’ve been exposed to the virus, even if you don’t have active symptoms.
["This test checks for past exposure to Hepatitis E virus, which can cause liver infection."]
Key facts at a glance
- LOINC
- 103092-3
- Short code
- Latex (rHev b) 3 IgE RAST
- Synonyms
- Latex (rHev b) 3 IgE RAST
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- rast
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects specific antibodies (IgG) your body creates after encountering Hepatitis E virus. Unlike acute infection tests, this one doesn’t show if you’re currently infected but confirms prior exposure. Antibodies develop weeks to months after exposure and remain in your system for years.
Why Might You Need This Test?
Your healthcare provider may order this test if you’ve traveled to regions with high Hepatitis E risk, have unexplained liver issues, or are in a group at higher risk (e.g., travelers, pregnant women, or those with weakened immune systems). It’s also used for screening before organ transplants or in outbreaks.
How Is the Test Performed?
A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it’s tested using an immunoassay method to detect IgG antibodies against Hepatitis E virus. Results are typically available within 2–3 business days.
What Are Possible Results?
Results are qualitative (positive/negative) and don’t provide a numeric value. A positive result means you likely had Hepatitis E in the past; a negative result suggests no detectable antibodies, meaning either you’ve never been exposed or your body cleared the virus without antibody production.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive test indicates past Hepatitis E infection, which can provide protection against future infections. However, it doesn’t guarantee immunity to all strains. This test is critical for identifying exposure history in high-risk populations, guiding preventive measures, or evaluating liver health in those with chronic conditions. A negative result doesn’t rule out past exposure if testing was done too early after infection.
Short name
Anti-Hepatitis E Virus IgG
Frequently asked questions
How Long Does It Take to Get Results?
What Does a Positive Result Mean?
Can I Get Hepatitis E Even If My Test Is Negative?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy