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Lipid Profile with Specific Subfraction Analysis (Cholesterol Subfractions: LDL, HDL, VLDL, and Triglycerides)

Published: August 9, 2026Updated: August 16, 2026

This test measures different types of fats (lipids) in your blood, including cholesterol and triglycerides, which help assess heart health and risk of cardiovascular disease.

Quick summary

["Understanding your lipid levels can help prevent or manage heart disease and high cholesterol."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22408-9
Short code
LCMV Ab Titr Ser
Synonyms
LCMV Ab Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have a family history of heart disease, high cholesterol, or other risk factors like high blood pressure. It’s also used to monitor treatment progress for conditions like high cholesterol or diabetes.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 12 hours before the test to get more accurate results. Bring any medications you’re currently taking.

How the Test Works

A small blood sample is drawn from a vein, usually in your arm. The blood is then analyzed in a lab to measure different lipid types, including LDL (bad cholesterol), HDL (good cholesterol), VLDL, and triglycerides.

What the Results Mean

Your results will show specific levels of these fats, helping your doctor determine if your cholesterol is within a healthy range or if you need lifestyle changes or medication.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High levels of LDL cholesterol and triglycerides, along with low HDL, increase the risk of heart disease and stroke. This test helps identify these risks early, allowing for timely interventions like diet changes, exercise, or medication to improve heart health.

Short name

Lipid Subfraction Panel

Frequently asked questions

How often should I get this test?
Typically, doctors recommend this test every 4–6 months if you have high cholesterol or other risk factors, or annually if your levels are already healthy.
What does a 'normal' result mean?
A 'normal' result doesn’t mean your cholesterol is perfectly fine—it means your levels fall within the general range for your age and health status. Your doctor will interpret results in relation to your specific needs.
Can I eat or drink anything before the test?
No, you should avoid food and liquids (except water) for 12 hours before the test to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy