Skip to content

Lactate Dehydrogenase (LDH) Activity in Serum/Plasma by Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of the enzyme lactate dehydrogenase (LDH), which helps assess cell damage or metabolic health in your blood.

Quick summary

["LDH levels can indicate tissue injury or metabolic processes in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13887-5
Short code
LDH2 CFr Ur Elph
Synonyms
LDH2 CFr Ur Elph
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
140
Ref high
280
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
83615
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is LDH Used For?

LDH is often checked to evaluate conditions affecting muscle, liver, heart, or red blood cells. Elevated levels may suggest damage to these tissues, while certain patterns can help diagnose specific disorders like certain cancers or infections.

How Is the Test Performed?

A blood sample is drawn, and the LDH enzyme activity is measured using electrophoresis, a technique that separates proteins based on size and charge. This helps determine the total LDH activity in your serum or plasma.

Common Conditions Monitored

LDH testing may be used in diagnosing or monitoring conditions such as myocardial infarction (heart attack), liver disease, muscle injuries, certain cancers (e.g., lymphoma), or hemolytic anemia (red blood cell breakdown).

What Does the Result Mean?

Results are not given in absolute numeric ranges here due to variability in testing methods and patient conditions. Your healthcare provider will interpret the result in relation to your symptoms and medical history.

Reference range

Adult: 140-280 U/LN/A

Specimen: urine

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated LDH levels can signal widespread tissue damage or metabolic stress, but interpretation depends on the context. For example, muscle injury may raise LDH, while certain cancers or infections may show distinct patterns. Always discuss results with your doctor to understand their relevance to your health.

Short name

LDH Activity

Frequently asked questions

How often is LDH tested?
LDH testing is often performed as part of routine blood work or when symptoms suggest tissue damage, metabolic issues, or underlying conditions like heart disease, liver problems, or cancer.
What are typical symptoms that might lead to LDH testing?
Symptoms that may prompt LDH testing include unexplained fatigue, muscle weakness, chest pain, jaundice (yellow skin), or signs of infection or cancer. Your doctor may also order it during routine check-ups or follow-up for known conditions.
Can LDH levels change with diet or exercise?
Yes, certain activities like intense exercise or muscle strain can temporarily raise LDH levels. However, diet alone typically does not significantly affect LDH unless it involves conditions like severe malnutrition or metabolic disorders.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy