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Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance calculation

Published: August 9, 2026Updated: August 17, 2026

This test measures your average blood sugar levels over the past 2–3 months and helps assess how well your kidneys filter waste from your urine.

Quick summary

["HbA1c tracks long-term blood sugar control, while urine creatinine clearance estimates kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2534-6
Short code
LDH Ur-cCnc
Synonyms
LDH Ur-cCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
140
Ref high
280
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83615
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have diabetes to monitor blood sugar control or if you have kidney concerns to evaluate kidney function. It combines two key measurements: HbA1c, which reflects long-term glucose levels, and urine creatinine clearance, which assesses how well your kidneys filter waste.

What to Expect Before the Test

For the HbA1c part, no special preparation is needed. For the urine creatinine clearance, you’ll collect all urine over a 24-hour period. Follow your provider’s instructions carefully to ensure accurate results.

What the Test Results Mean

HbA1c results help determine if your diabetes is well-managed, while urine creatinine clearance shows kidney function. Together, they provide a fuller picture of your health status.

Common Causes of Abnormal Results

High HbA1c levels may indicate poor blood sugar control, while abnormal urine creatinine clearance could signal kidney issues. Both results may also be affected by recent illness, dehydration, or certain medications.

Reference range

Adult: 140-280 U/LN/A

Specimen: urine

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HbA1c + Urine Creatinine Clearance

Frequently asked questions

How often should I get this test?
Typically, HbA1c is checked every 3–6 months for diabetes management. Urine creatinine clearance may be checked periodically if you have kidney concerns or are at risk for kidney disease.
Can I eat or drink before the urine collection?
Yes, but avoid excessive fluids or foods that could alter urine composition. Follow your provider’s specific instructions for the 24-hour urine collection.
What if my results are out of range?
If your HbA1c is high, your provider may recommend lifestyle changes, medication adjustments, or closer monitoring. If creatinine clearance is low, they may suggest kidney function tests or treatments to support your kidneys.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy