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Low-Density Lipoprotein Cholesterol, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures LDL (“bad”) cholesterol in blood, helping assess cardiovascular risk and guide cholesterol treatment.

Quick summary

["LDL cholesterol is one of the main blood markers used to estimate the risk of heart attack and stroke."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91110-7
Short code
LDL6c SerPl-mCnc
Synonyms
LDL6c SerPl-mCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of low-density lipoprotein cholesterol in your blood. LDL cholesterol is a type of cholesterol that can build up in artery walls and contribute to narrowing of the arteries.

Why might I need this test?

The test may be used to assess your risk of heart attack, stroke, and other cardiovascular problems. It is commonly part of a lipid panel and may be repeated to monitor treatment for high cholesterol.

How is the test performed?

A blood sample is collected, and the serum or plasma portion is analyzed to determine the LDL cholesterol concentration. Depending on the laboratory, the result may be measured directly or calculated from other cholesterol values.

How do I prepare for the test?

Follow any instructions from your healthcare professional. Some laboratories request fasting for 9 to 12 hours, while others do not, so confirm the preparation requirements before your appointment.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A high LDL cholesterol concentration may indicate an increased risk of plaque buildup and cardiovascular disease. Unusually low LDL cholesterol can have several causes, including genetic factors, dietary changes, medications, or certain medical conditions, so it should be interpreted alongside your overall health and medical history.

Short name

LDL cholesterol

Frequently asked questions

Is LDL cholesterol the same as “bad” cholesterol?
Yes. LDL cholesterol is often called “bad” cholesterol because elevated levels can contribute to plaque buildup in arteries.
Does this test require fasting?
It depends on the laboratory and the other tests being performed. Ask your healthcare professional whether you should fast before the blood draw.
What can cause a high LDL cholesterol result?
Common contributors include an unhealthy diet, genetic susceptibility, obesity, reduced physical activity, smoking, and certain medications or health conditions. Your healthcare professional can help determine which factors apply to you.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy