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Low-Density Lipoprotein Cholesterol, Serum/Plasma — Qualitative

Published: August 9, 2026Updated: August 16, 2026

A blood test that categorically evaluates LDL, commonly called “bad” cholesterol, to help assess cardiovascular risk.

Quick summary

["LDL cholesterol helps assess the buildup of fatty plaque in the arteries and your risk of heart disease or stroke."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48635-7
Short code
LDLc A SerPl Ql
Synonyms
LDLc A SerPl Ql
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures or categorically reports low-density lipoprotein (LDL) cholesterol in a blood sample. LDL is often called “bad” because high levels can contribute to fatty plaque buildup in arteries.

Why might I need this test?

A clinician may order this test to evaluate your risk of heart disease and stroke, monitor cholesterol treatment, or investigate an abnormal cholesterol result. It is often interpreted with total cholesterol, HDL cholesterol, triglycerides, and your medical history.

How is the test performed?

A blood sample is collected and analyzed in a laboratory using a validated cholesterol assay. A qualitative result provides a category rather than an exact LDL concentration.

How do I prepare for the test?

Fasting is often unnecessary, but follow any instructions from your clinician, especially if you have recently changed your diet, exercise routine, or cholesterol medication. Drinking water is usually acceptable unless you receive different instructions.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated LDL result may indicate increased risk of plaque-related cardiovascular disease, particularly when other risk factors are present. Lower LDL levels generally reflect a lower risk or the effect of lifestyle changes or treatment. Your clinician will interpret the result using your overall cholesterol profile, medical history, and risk factors.

Short name

LDL cholesterol

Frequently asked questions

Why is LDL cholesterol called bad cholesterol?
LDL can carry cholesterol into artery walls, where it may contribute to plaque buildup. Higher LDL levels are generally associated with greater cardiovascular risk.
Does this test require fasting?
Fasting is often not required, although some clinicians request it for a complete lipid profile. Follow the specific preparation instructions provided with your order.
What can change my LDL cholesterol?
Diet, physical activity, weight, smoking, genetics, and certain medications can affect LDL levels. Repeated testing may be used to monitor changes over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy