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Low-Density Lipoprotein Cholesterol, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures LDL (“bad”) cholesterol in blood to help assess cardiovascular risk and guide cholesterol management.

Quick summary

["Higher LDL cholesterol can increase the risk of heart attack and stroke."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35198-1
Short code
LDLc SerPl-msCnc
Synonyms
LDLc SerPl-msCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of low-density lipoprotein (LDL) cholesterol in your blood. LDL is often called “bad” cholesterol because it can build up in artery walls.

Why might I need this test?

Your clinician may order this test to assess your risk of heart disease and stroke, evaluate cholesterol treatment, or monitor changes in your cholesterol levels.

How is the test performed?

A blood sample is collected, usually from a vein in your arm. The sample is analyzed in a laboratory to determine the concentration of LDL cholesterol.

How do I prepare for the test?

Fasting for about 9 to 12 hours may be required, depending on the test and your clinician’s instructions. Water is generally encouraged, and you should ask whether any medications or dietary changes need special handling.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher LDL cholesterol level may indicate an increased risk of plaque buildup in the arteries, which can contribute to heart attack and stroke. Lower levels generally reflect a more favorable cardiovascular risk profile, but the meaning of your result depends on your overall health, medical history, and other risk factors.

Short name

LDL Cholesterol

Frequently asked questions

Is LDL cholesterol the same as “bad” cholesterol?
Yes. LDL is commonly called “bad” cholesterol because high levels can contribute to fatty plaque buildup in arteries.
Do I need to fast before this test?
Sometimes. Your clinician may ask you to fast for 9 to 12 hours, so follow the instructions provided with the test order.
Can I lower LDL cholesterol?
Often, yes. Eating habits, physical activity, weight management, and medications prescribed by your clinician may help reduce LDL cholesterol and cardiovascular risk.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy