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Total Cholesterol in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood serum, a key part of your lipid profile that helps assess heart health.

Quick summary

["Cholesterol levels help determine your risk for cardiovascular disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17083-7
Short code
LDL Fld-mCnc
Synonyms
LDL Fld-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It Matters in Your Health

Cholesterol is a waxy substance your body needs to make hormones, vitamin D, and cell membranes. However, too much cholesterol in your blood can build up in your arteries, increasing the risk of heart disease or stroke. This test helps doctors monitor your cholesterol levels to guide lifestyle and treatment recommendations.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. If you’re on a blood thinner, let your healthcare provider know before the test.

How the Results Are Used

Your results will be compared to general reference ranges to identify whether your cholesterol levels are within a healthy range or if further action is needed. Your doctor may use these results to adjust medications, recommend dietary changes, or suggest exercise programs.

Common Questions About This Test

This test is typically ordered as part of a routine lipid panel to assess cardiovascular risk, especially if you have a family history of high cholesterol, diabetes, or high blood pressure.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Cholesterol

Frequently asked questions

What does a high total cholesterol level mean?
A high total cholesterol level suggests an increased risk of heart disease or stroke. Your doctor may recommend lifestyle changes, medications, or further testing to manage it.
How often should I get this test?
Your doctor will determine how often you need this test based on your overall health, risk factors, and medical history. Typically, adults with no risk factors may get it every 4–6 years, while those with risk factors may need it more frequently.
Can diet affect my cholesterol test results?
Yes, diet plays a major role. Eating foods high in saturated fats, trans fats, and cholesterol can raise your levels, while a diet rich in fruits, vegetables, whole grains, and healthy fats (like olive oil) can help lower them. Avoid eating before the test if instructed by your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy