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Total Cholesterol, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, which includes both low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol, as well as triglycerides and other fats.

Quick summary

["Cholesterol levels help assess your risk for heart disease and other health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26821-9
Short code
LDL Fld Ql
Synonyms
LDL Fld Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Cholesterol Levels Tell Us About Your Health

Cholesterol is a type of fat that your body needs for many important functions, such as building cell membranes and producing hormones. However, having too much cholesterol in your blood can increase your risk of developing heart disease or stroke. This test helps healthcare providers understand your overall cholesterol profile and whether you may need lifestyle changes or medication to manage your health.

Why This Test Might Be Ordered

Your healthcare provider may order this test as part of a routine checkup, to monitor your cholesterol levels over time, or to evaluate risk factors for heart disease. It’s often done alongside other tests, such as HDL cholesterol and triglycerides, to get a full picture of your lipid profile.

What to Expect Before the Test

For this test, a small amount of blood is drawn from a vein in your arm. You may feel a slight pinch when the needle is inserted, but most people find it over quickly. No special preparation is needed, though you should avoid eating or drinking anything for at least 12 hours before the test if it’s part of a fasting lipid panel.

What the Results Mean

The results of this test provide a single number representing your total cholesterol level. While this number alone doesn’t tell the whole story, it’s a key part of assessing your cardiovascular health. Your healthcare provider will use these results along with other factors, such as HDL cholesterol and triglycerides, to determine if your levels are within a healthy range or if further action is needed.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance of Cholesterol Levels

Short name

Total Cholesterol

Frequently asked questions

How long does it take to get my cholesterol test results back?
Results for this test are typically available within a few days to a week, depending on your lab and healthcare provider. If your test is part of a larger lipid panel, results may take slightly longer to compile. Follow up with your provider to discuss your results and any next steps.
What does a high total cholesterol level mean?
A high total cholesterol level can indicate an increased risk of developing heart disease or other cardiovascular conditions. While it doesn’t always mean you need immediate action, it may prompt your healthcare provider to recommend lifestyle changes, such as diet, exercise, or medication, to help lower your cholesterol.
Can I lower my cholesterol naturally?
Yes, there are several natural ways to help manage cholesterol levels, including eating a heart-healthy diet (such as the Mediterranean diet), staying physically active, maintaining a healthy weight, and avoiding smoking. Some people may also benefit from supplements like omega-3 fatty acids or plant sterols, but always check with your provider before starting any new supplement.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy