Low-Density Lipoprotein Cholesterol (LDL-C) from Serum
This test measures the amount of LDL cholesterol in your blood serum, a type of fat that can build up in your arteries over time.
["LDL cholesterol is linked to heart disease risk; lower levels are generally safer."]
Key facts at a glance
- LOINC
- 96735-6
- Short code
- LDL med Ser-sCnc
- Synonyms
- LDL med Ser-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83721
- SNOMED
- 113079007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
LDL cholesterol is often called the 'bad' cholesterol because high levels increase your risk of plaque buildup in your arteries, which can lead to heart attacks or strokes. Your doctor may order this test to assess your cardiovascular health, especially if you have risk factors like high blood pressure, diabetes, or a family history of heart disease.
What to Expect Before the Test
No special preparation is needed, but you may be asked to fast for 8–12 hours before the test. Bring any medications you’re currently taking, as some (like statins) may affect your results. Your blood will be drawn from a vein in your arm, similar to a routine blood test.
What the Results Mean
Results help doctors determine if your LDL cholesterol is within a healthy range. While exact reference ranges vary by lab, higher levels may signal the need for lifestyle changes or medications to lower cholesterol. Your doctor will discuss these findings with you in detail.
Common Causes of Abnormal Results
High LDL cholesterol can result from poor diet (high in saturated fats), lack of physical activity, obesity, smoking, or genetic factors. Conditions like diabetes or hypothyroidism may also influence levels. Low LDL may occur if your body naturally breaks down cholesterol efficiently or if certain medications are affecting it.
Reference range
Optimal: <100 mg/dLN/A
Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
LDL Cholesterol (Serum)
Frequently asked questions
How often should I get this test?
Can diet alone lower LDL cholesterol?
Do I need to avoid certain foods before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy