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Serum/plasma lipid profile with specific fraction measurements (e.g., cholesterol, triglycerides, HDL, LDL, VLDL, and phospholipids)

Published: August 9, 2026Updated: August 16, 2026

This test measures key components of your blood lipids, including cholesterol and fat types, to assess heart health and metabolic function.

Quick summary

["Helps identify risks for heart disease and high cholesterol by showing how different fats circulate in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15122-5
Short code
LDL MFr SerPl
Synonyms
LDL MFr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Your blood sample will be analyzed for several lipid-related measurements, including total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), and phospholipids. These components help evaluate how fats are distributed in your bloodstream.

Why It Matters for Your Health

High levels of certain fats (like LDL) or low HDL can increase your risk for heart disease, stroke, or other cardiovascular issues. This test helps doctors monitor and manage these risks, especially if you have a family history of high cholesterol or related conditions.

When You Might Need This Test

Your doctor may recommend this test if you have risk factors for heart disease (e.g., high blood pressure, obesity, diabetes), if you’re being evaluated for high cholesterol, or as part of routine check-ups, especially after age 20.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 12 hours before the test if measuring triglycerides. Wear comfortable clothing for a blood draw, and let your doctor know about any medications or recent illnesses.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lipid panel with detailed fractions

Frequently asked questions

How do I know if my lipid test results are within a healthy range?
Your doctor will compare your results to standard guidelines and consider your overall health, including age, gender, and other conditions. For example, higher LDL or triglycerides may signal the need for lifestyle changes or medication.
Can I lower my cholesterol naturally?
Yes! Diet (e.g., more fiber, healthy fats like olive oil), exercise, and avoiding smoking can help. If needed, your doctor may also prescribe medications to manage cholesterol levels.
What if my test results are abnormal?
If your results show elevated lipids, your doctor will discuss next steps, which may include further testing, lifestyle adjustments, or treatment options tailored to your needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy