Oxidized Low-Density Lipoprotein (LDL), Serum/Plasma — Concentration
This blood test measures oxidized LDL particles, a form of LDL that may contribute to cholesterol buildup in artery walls.
["Elevated oxidized LDL may indicate increased cardiovascular risk, but the result must be interpreted with other risk factors."]
Key facts at a glance
- LOINC
- 54238-1
- Short code
- LDL.oxidized SerPl-aCnc
- Synonyms
- LDL.oxidized SerPl-aCnc
- Category
- lipid
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83721
- SNOMED
- 113079007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures the amount of oxidized low-density lipoprotein (LDL) in a blood sample. LDL is a cholesterol-carrying particle, and oxidation is a change that may make it more likely to contribute to plaque in the arteries.
Why might I need this test?
Oxidized LDL testing may be used as part of a broader assessment of cardiovascular risk, especially in people with high cholesterol, a family history of early heart disease, diabetes, or other risk factors. It does not replace standard cholesterol testing or a clinician's overall risk assessment.
How is the test performed?
A blood sample is collected and separated into serum or plasma. A laboratory then measures the amount of oxidized LDL using a validated testing method. Your healthcare professional will interpret the result along with your other cholesterol values and medical history.
How do I prepare for the test?
No special preparation is commonly required, although the laboratory may request fasting. Follow any instructions from your healthcare professional and do not stop prescribed medicines unless your clinician tells you to do so.
Reference range
Optimal: <100 mg/dLN/A
Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A higher amount of oxidized LDL may indicate a greater burden of cholesterol particles capable of promoting inflammation and plaque formation in the arteries. This can be associated with increased risk of atherosclerotic heart disease, heart attack, and stroke. An isolated result does not diagnose heart disease, and laboratory reference ranges can vary.
Short name
Oxidized LDL
Frequently asked questions
Is oxidized LDL the same as LDL cholesterol?
Is this a routine cholesterol test?
Can I lower oxidized LDL at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy