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Oxidized Low-Density Lipoprotein (OxLDL), Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of oxidized LDL in serum or plasma. It is not the same test as standard LDL cholesterol and may be used to assess cardiovascular risk.

Quick summary

["This blood test measures oxidized LDL, a form of cholesterol that may contribute to vascular inflammation and plaque formation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111519-5
Short code
LDL.oxidized SerPl-mCnc
Synonyms
LDL.oxidized SerPl-mCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of oxidized low-density lipoprotein (OxLDL) in serum or plasma. Oxidized LDL is a form of LDL cholesterol that has undergone oxidative modification and may promote inflammation in blood vessel walls.

Why might I need this test?

OxLDL testing may be ordered as part of a cardiovascular risk assessment or by a specialist evaluating lipid-related concerns. It may provide additional information alongside standard cholesterol tests, but it does not replace them.

How is the test performed?

A blood sample is collected, and serum or plasma is separated for laboratory analysis. The laboratory measures the concentration of oxidized LDL using a validated assay.

How do I prepare for the test?

No special preparation is usually required for this test. If your clinician or laboratory requests fasting, follow those instructions and tell the healthcare team if you have recently taken cholesterol-lowering medicines.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Oxidized LDL

Frequently asked questions

Is oxidized LDL the same as LDL cholesterol?
No. Standard LDL cholesterol measures the total amount of LDL in the blood, while this test specifically measures the fraction of LDL that has been oxidized.
Does a high oxidized LDL result mean I have heart disease?
No. A high result may suggest increased cardiovascular risk, but it does not confirm that heart disease is present. Your clinician will consider it along with other cholesterol results, symptoms, and risk factors.
Do I need to fast before this test?
Fasting is not generally required unless the ordering clinician or laboratory specifically requests it. Confirm the preparation instructions before your blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy