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Lipoprotein(a) [Lp(a)] concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-related protein that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher cardiovascular risk; knowing your levels helps assess your heart health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9620-6
Short code
LDL Plr-mCnc
Synonyms
LDL Plr-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Is Lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it shares some traits with cholesterol, it behaves differently in the body and is associated with a higher risk of clotting and heart disease. This test specifically measures the mass concentration of Lp(a) in your bloodstream.

Why Is This Test Done?

Your healthcare provider may order this test if you have a family history of heart disease, stroke, or blood clots, or if you have conditions like high cholesterol or atherosclerosis. It may also be used to monitor risk in people with known cardiovascular issues or those undergoing treatments to manage cholesterol levels.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then sent to a lab for analysis using a specialized immunoassay method to measure the exact amount of lipoprotein(a) in your blood.

What Does the Test Result Mean?

Higher levels of Lp(a) may indicate an increased risk of cardiovascular events like heart attacks or strokes. While there’s no single reference range for Lp(a), very high levels are often considered a risk factor. Your results will be discussed with your healthcare provider to help guide further evaluation or treatment options.

Reference range

Optimal: <100 mg/dLN/A

Specimen: fluid

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lp(a) level

Frequently asked questions

What Are Common Causes or Factors Affecting Lp(a) Levels?
Lipoprotein(a) levels are generally stable over time and are influenced by genetics—meaning they’re often inherited. Unlike cholesterol, which can sometimes be lowered with diet and exercise, there are currently no widely accepted lifestyle changes or medications specifically to lower Lp(a). However, your healthcare provider may discuss other cardiovascular risk factors you can manage, such as blood pressure or cholesterol levels.
Is There a Way to Lower Lp(a) Levels?
Research is ongoing to find effective ways to lower Lp(a) levels. Some experimental treatments, such as monoclonal antibodies, are being studied but are not yet widely available. For now, managing other cardiovascular risks—like quitting smoking, maintaining a healthy weight, and controlling blood pressure—can support overall heart health.
How Often Should I Get This Test?
Your healthcare provider will determine the frequency of this test based on your individual risk profile. If you have a high risk of cardiovascular disease, they may recommend testing every few years or more often, depending on your health status and treatment plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy