Low-Density Lipoprotein Cholesterol (LDL-C) Calculated from Serum Lipid Profile
This test calculates your LDL cholesterol level using results from your total cholesterol, HDL cholesterol, and triglyceride measurements. LDL cholesterol is often called the 'bad' cholesterol because high levels may increase your risk of heart disease.
["LDL cholesterol is a key measure of your heart health and helps determine your risk for cardiovascular issues."]
Key facts at a glance
- LOINC
- 9346-8
- Short code
- LDL SerPl Calc-mCnc
- Synonyms
- LDL SerPl Calc-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- calculated
- CPT
- 83721
- SNOMED
- 113079007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How LDL Cholesterol is Calculated
Your LDL cholesterol is derived from a formula applied to your blood lipid test results, including total cholesterol, HDL cholesterol, and triglycerides. This calculation assumes your blood sample was drawn in the morning on an empty stomach for most accuracy.
Why LDL Cholesterol Matters
LDL cholesterol carries cholesterol to your arteries. Over time, high levels can build up as plaque, narrowing arteries and increasing the risk of heart attacks or strokes. Your doctor may recommend lifestyle changes or medications if your LDL cholesterol is too high.
What to Expect Before Your Test
No special preparation is needed for this calculated test, but your doctor may ask you to fast for 9–12 hours before your blood draw to get the most accurate results. Wear comfortable clothing and bring any medications you’re currently taking.
What to Expect During Your Test
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure usually takes just a few minutes. You can resume normal activities immediately afterward.
Reference range
Optimal: <100 mg/dLN/A
Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
LDL Cholesterol (Calculated)
Frequently asked questions
Why is LDL cholesterol important in my health plan?
How often should I get this test?
Can diet or exercise lower my LDL cholesterol?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy