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Low-Density Lipoprotein Cholesterol (LDL-C) Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of LDL cholesterol in your blood serum, a key type of fat that can build up in your arteries over time.

Quick summary

["LDL cholesterol is often called 'bad cholesterol' because high levels may increase your risk of heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92715-2
Short code
LDL very small-a Ser-sCnc
Synonyms
LDL very small-a Ser-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to assess your risk of heart disease, monitor cholesterol levels after treatment, or check for conditions like high cholesterol or metabolic syndrome. It’s often part of a broader lipid panel that also includes HDL and total cholesterol.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a full lipid profile. Bring any medications you’re taking to your appointment.

How the Test Works

A blood sample is drawn from a vein, typically in your arm. The serum (liquid part of blood after clotting) is then analyzed to measure LDL cholesterol concentration using a specialized laboratory method.

What the Results Mean

Results help determine whether your LDL cholesterol is within a healthy range or if lifestyle or medical interventions may be needed. While exact ranges vary by age, gender, and health status, high levels may prompt further evaluation.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High LDL cholesterol is strongly linked to plaque buildup in arteries, increasing the risk of heart attack, stroke, or peripheral artery disease. Regular monitoring helps manage risk factors and guide treatment decisions, such as diet, exercise, or medication.

Short name

LDL Cholesterol Level

Frequently asked questions

How often should I get this test?
Your doctor will recommend how often to check your LDL cholesterol based on your overall health, risk factors, and treatment plan. Typically, adults with high risk may get it every 1–2 years, while others may need it less frequently.
What can affect my LDL cholesterol levels?
Several factors influence LDL cholesterol, including diet (e.g., saturated fats), physical activity, genetics, smoking, and weight. Certain medications (like statins) can also lower LDL levels.
Do I need to do anything special after the test?
No special follow-up is needed unless your results are abnormal. If you have questions about your results, discuss them with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy