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Low-Density Lipoprotein Cholesterol (LDL-C) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of LDL cholesterol in your blood, a type of fat that can build up in your arteries and increase your risk of heart disease.

Quick summary

["LDL cholesterol is a key marker for heart health and cardiovascular risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92714-5
Short code
LDL very small-b Ser-sCnc
Synonyms
LDL very small-b Ser-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

LDL cholesterol is often called the 'bad' cholesterol because high levels can contribute to plaque buildup in your arteries, which may restrict blood flow and increase the risk of heart attacks or strokes. This test helps doctors assess your overall cardiovascular health and guide treatment plans if needed.

What to Expect Before the Test

No special preparation is usually required, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Wear a loose-fitting shirt for easy access to your arm.

How the Test Works

A small amount of blood is drawn from a vein in your arm. The blood is then sent to a lab where it is analyzed to determine your LDL cholesterol concentration using a blood test method.

What the Results Mean

Results are typically reported as a numerical value representing your LDL cholesterol level. While exact reference ranges vary by lab, higher levels may indicate increased risk of artery damage, while lower levels may suggest better cardiovascular health. Your doctor will interpret your results in the context of your overall health.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

LDL Cholesterol Level

Frequently asked questions

What Does a High LDL Cholesterol Level Indicate?
A high LDL cholesterol level is associated with an increased risk of developing heart disease or having a heart attack or stroke. Your doctor may recommend lifestyle changes, medications, or other treatments to help lower your LDL cholesterol if it is too high.
What Does a Low LDL Cholesterol Level Indicate?
A low LDL cholesterol level may suggest a lower risk of artery damage, but it is not a guarantee of good cardiovascular health. Other factors, such as diet, exercise, and overall health, also play a role. Your doctor will consider all aspects of your health when making recommendations.
How Often Should I Get This Test?
Your doctor will determine how often you need this test based on your age, overall health, and risk factors for heart disease. Typically, adults with no known heart disease may get this test every 4–6 years, while those with risk factors may need it more frequently.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy