Low-Density Lipoprotein (LDL) Substance Concentration in Serum
This test measures the amount of LDL cholesterol, a type of fat in your blood, which can contribute to plaque buildup in your arteries over time.
["LDL cholesterol is an important marker for heart health and risk of cardiovascular disease."]
Key facts at a glance
- LOINC
- 92712-9
- Short code
- LDL very small-d Ser-sCnc
- Synonyms
- LDL very small-d Ser-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83721
- SNOMED
- 113079007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
LDL cholesterol is often called the 'bad' cholesterol because high levels may increase your risk of developing conditions like heart disease or stroke. Your doctor may recommend this test if you have risk factors for heart disease, such as high blood pressure, diabetes, or a family history of heart problems.
When You Might Need This Test
You may be asked to have this test if your doctor wants to monitor your cholesterol levels, check for high cholesterol, or evaluate your risk for cardiovascular issues. It’s often part of a broader cholesterol panel that includes other types of cholesterol and triglycerides.
How the Test Works
A small blood sample is drawn from your arm, usually while you’re sitting comfortably. The blood is then sent to a lab where it’s analyzed to measure the LDL cholesterol concentration. The results help your healthcare provider assess your lipid profile.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a full lipid panel. If you’re unsure, ask your doctor or lab technician for specific instructions.
Reference range
Optimal: <100 mg/dLN/A
Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
LDL Cholesterol (Serum)
Frequently asked questions
High LDL cholesterol levels can lead to the buildup of fatty deposits in your arteries, which may restrict blood flow and increase the risk of heart attacks or strokes. Your doctor may recommend lifestyle changes, medications, or other treatments if your LDL levels are too high.
What does a high or low LDL level mean?
Can diet or exercise affect LDL cholesterol levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy