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Lead and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

A 24-hour urine test that measures lead excretion and urine creatinine, which helps evaluate the adequacy of the urine collection.

Quick summary

["This test can identify ongoing lead exposure and may be used to assess exposure in people who work around lead or live in an area with possible contamination."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29943-8
Short code
Lead/Creat 24h Ur
Synonyms
Lead/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of lead released into the urine over 24 hours. Urine creatinine is also measured to help assess how concentrated the collection is and whether the full urine sample was collected.

Why might I need this test?

A urine lead test may be recommended for people with occupational lead exposure, contact with contaminated soil, water, paint, pottery, or certain supplements. It may also be used to monitor the effectiveness of exposure-control measures or lead treatment.

How is the test performed?

Urine is collected into a special container for a full 24-hour period. All urine produced during that time is saved, the container is sealed and labeled, and the sample is returned to the laboratory for analysis.

How do I prepare for the test?

Follow the laboratory's collection instructions exactly, including the starting time, whether to refrigerate the container, and how to record or discard urine collected during the period. Do not change your diet, medications, or exposure habits unless your clinician instructs you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-hour urine lead

Frequently asked questions

Why is urine creatinine included?
Urine creatinine helps show how concentrated the urine is and whether a 24-hour collection appears adequate. It is commonly used when interpreting a urine lead result.
What can cause high urine lead levels?
Common sources include workplace exposure, lead-contaminated soil or dust, old paint, contaminated water, and some imported products or supplements. The source of exposure should be discussed with a healthcare professional.
Does an abnormal result mean I have lead poisoning?
A high result suggests lead exposure but does not by itself establish lead poisoning or the severity of harm. A clinician can interpret the result and may recommend blood testing, exposure measures, or follow-up.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy