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Lead in Serum/Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lead in your blood, which can help identify exposure to this heavy metal that may harm your body over time.

Quick summary

["Lead exposure can affect your nervous system, kidneys, and other organs—this test helps monitor potential risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10912-4
Short code
Lead SerPl-mCnc
Synonyms
Lead SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’ve been exposed to lead (e.g., from paint, dust, or industrial settings), have symptoms like headaches, fatigue, or abdominal pain, or if you’re at higher risk (e.g., children, workers in certain industries). It can also be part of routine screening for certain conditions.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Bring any medications or supplements you’re taking to discuss with your provider.

How the Test Works

A blood sample is taken from a vein in your arm. The sample is then analyzed in a lab to measure lead levels using a sensitive detection method.

What the Results Mean

High lead levels may indicate recent or ongoing exposure. Your provider will interpret results in the context of your symptoms, medical history, and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Lead Level (Serum/Plasma)

Frequently asked questions

What causes lead exposure?
Lead exposure can come from contaminated food, water, dust, or environmental sources like old paint, pipes, or certain hobbies (e.g., soldering). Workplace hazards or living in areas with poor air quality may also increase risk.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will discuss them with you.
Can lead levels be affected by diet?
Dietary factors like calcium, vitamin D, or zinc may influence lead absorption, but they don’t change the test result itself. Avoiding lead-containing products (e.g., some candies, cosmetics) can help reduce exposure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy