Lead in Tissue (24-Hour Integrated)
This test measures the amount of lead stored in your body tissues over a 24-hour period, helping assess long-term exposure.
["Long-term lead exposure can be tracked by checking stored lead levels in your body."]
Key facts at a glance
- LOINC
- 52890-1
- Short code
- Lead Tiss-sCnt
- Synonyms
- Lead Tiss-sCnt
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Lead is a toxic metal that can accumulate in your body over time, especially in children and pregnant individuals. This test helps identify chronic exposure that standard urine or blood tests might miss. Lead can interfere with brain development, cause developmental delays, and increase risks for heart and kidney problems. Early detection is key to preventing harm.
What to Expect Before the Test
No special preparation is needed for this test. You’ll have a small sample of tissue (usually from a biopsy) analyzed for lead content. This is typically done under local anesthesia and is generally safe. Follow-up instructions from your healthcare provider will guide you on any dietary or activity restrictions post-procedure.
What the Results Mean
Results show the average lead concentration in your tissues over 24 hours. Higher levels may indicate ongoing exposure or poor elimination. Your doctor will interpret results in the context of your medical history, symptoms, and other tests. Elevated levels may prompt further investigation or treatment recommendations.
Common Causes of Elevated Lead Levels
Chronic exposure can come from contaminated food/water, dust, or environmental sources like old paint or pipes. Occupational exposure (e.g., battery manufacturing) or living in areas with high lead pollution may also contribute. Children are more vulnerable due to higher absorption rates and developing systems.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
24-Hour Lead Tissue Content
Frequently asked questions
How is this test different from a urine lead test?
Can lead levels be lowered without treatment?
Is this test painful or risky?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy