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Urine Lead Mass Concentration (24-hour collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of lead found in your urine over a 24-hour period. Lead is a heavy metal that can build up in the body and may cause health problems, especially in children.

Quick summary

["A 24-hour urine lead test helps assess long-term exposure to lead in your environment or from certain medical treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5675-4
Short code
Lead Ur Ql
Synonyms
Lead Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if you have symptoms of lead poisoning (such as fatigue, headaches, or developmental delays in children), if you work in an environment with lead exposure (e.g., construction, battery manufacturing), or if you’ve been exposed to lead through contaminated water, food, or supplements. It can also be used to monitor lead levels in people receiving certain treatments, like chelation therapy.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after midnight on one day and ending just before midnight the next. Follow your healthcare provider’s instructions carefully to ensure accurate results. Drink plenty of water to help flush lead out of your body.

What to Expect During the Test

You’ll provide a single urine sample at the end of the 24-hour period, which will be tested in a lab. No special preparation is needed beyond collecting your urine as directed.

What the Results Mean

Higher-than-normal lead levels in urine may indicate ongoing exposure to lead. Your doctor will interpret the results in the context of your symptoms, medical history, and other tests. Very high levels can cause serious health issues, while low levels may not require immediate action but should be monitored.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Lead

Frequently asked questions

How often should I get this test if I have a history of lead exposure?
Your doctor will determine how often you need retesting based on your current lead levels, symptoms, and exposure risk. Regular monitoring may be recommended if you continue to be exposed to lead or if your levels remain elevated.
Can I drink coffee or other beverages during the 24-hour urine collection?
Yes, you can drink water, coffee, or other fluids as long as you collect all urine produced during the 24-hour period. Avoid excessive caffeine, which may slightly alter lead excretion, unless instructed otherwise by your provider.
What if I miss collecting urine at the end of the 24-hour period?
If you miss the final collection, you’ll need to restart the 24-hour period from the beginning. Follow your healthcare provider’s instructions to ensure accurate results, as incomplete collections can affect the test’s reliability.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy