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Leishmania IgG Antibody, Serum (Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the Leishmania parasite in your blood, which may indicate past or current infection with this organism. Leishmania causes a range of diseases, primarily affecting the skin, mucous membranes, and internal organs.

Quick summary

["This test helps diagnose or monitor suspected Leishmania infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
52985-9
Short code
Leishmania IgG Titr Ser IF
Synonyms
Leishmania IgG Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test measures the presence of Immunoglobulin G (IgG) antibodies against Leishmania antigens in your serum. IgG antibodies are typically produced after an initial infection and can remain in your system for a longer period, helping the immune system remember the pathogen for future protection. This test is used to detect past exposure to the parasite, which may not always cause symptoms but can still be detected through antibody testing.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms suggestive of Leishmania infection, such as skin sores, fever, fatigue, or organ involvement (e.g., spleen or liver enlargement). It may also be used in areas where Leishmania is endemic to screen for exposure, especially in individuals with risk factors like travel to infected regions or certain occupational exposures.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. If you are pregnant, have a bleeding disorder, or take blood-thinning medications, inform your healthcare provider beforehand.

What to Expect During the Test

The blood sample is collected and sent to a laboratory for analysis using an immunoassay method. This process typically involves mixing the serum with Leishmania-specific antigens and detecting the presence of IgG antibodies through a chemical reaction. Results are usually available within a few days.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Leishmania IgG Antibody

Frequently asked questions

Can this test detect active Leishmania infection?
No, this test specifically measures IgG antibodies, which are produced after an initial infection and can remain in your system for months or years. It does not directly detect active infection, which would typically require additional tests like PCR or culture for the parasite itself.
What does a positive result mean?
A positive result indicates that your body has produced antibodies against Leishmania, suggesting past exposure. This does not always mean you currently have an active infection but may indicate a history of infection. Consult your healthcare provider to discuss symptoms and further testing if needed.
Are there any risks or side effects from this blood test?
The most common side effect is a slight bruise, redness, or minor pain at the injection site, which usually fades within a day or two. Rarely, there may be a reaction to the needle or blood draw, such as dizziness or fainting. Inform your healthcare provider if you experience any unusual symptoms after the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy