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Total Protein in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein found in your blood serum, which includes albumin and other proteins like globulins.

Quick summary

["Your blood protein levels help assess overall health, kidney function, and nutritional status."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61246-5
Short code
Lemon IgE/IgE total %
Synonyms
Lemon IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Doctors may order this test to check for conditions affecting protein production, such as liver disease, kidney problems, or malnutrition. It can also help diagnose conditions like chronic inflammation, infections, or certain cancers.

What to Expect During the Test

A small blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and doesn’t require special preparation.

Common Conditions Monitored

High protein levels might suggest dehydration, severe burns, or certain types of cancer. Low protein levels could indicate liver disease, kidney failure, or malnutrition.

Factors That Could Affect Results

Factors like dehydration, recent illness, or certain medications can influence protein levels. Avoiding blood-donating activities or strenuous exercise before the test can help ensure accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Serum Protein

Frequently asked questions

How long will it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab. Follow-up with your healthcare provider if you have any questions about the results.
Can I eat or drink before this test?
You can eat and drink normally before this test unless instructed otherwise by your doctor. No special preparation is needed.
What does it mean if my protein levels are abnormal?
Abnormal results should be discussed with your healthcare provider. They can help determine if further testing or treatment is needed based on your overall health and symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy