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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7455-9
Short code
Lemon IgG Qn
Synonyms
Lemon IgG Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a creatinine test to monitor kidney health, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used before certain procedures, to check for kidney disease, or to evaluate kidney function in people with diabetes or high blood pressure.

What Does a High or Low Level Mean?

High levels may indicate kidney problems, dehydration, or conditions that reduce blood flow to the kidneys. Low levels could suggest overhydration, muscle breakdown, or liver disease, though this is less common. Your doctor will interpret results in relation to your overall health.

Sample Collection and Preparation

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab for testing. If you’re on dialysis or have certain medications, your doctor may advise timing your test around your treatment schedule to avoid interference.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications you’re taking, especially those that affect kidney function (e.g., NSAIDs, certain antibiotics). Avoid strenuous activity or eating heavy meals before the test if instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

A creatinine test is a key part of a kidney function panel, often paired with blood urea nitrogen (BUN) to assess how well your kidneys are filtering waste. It’s also used to monitor progression of chronic kidney disease, guide dialysis timing, or evaluate response to treatments for conditions like heart failure or severe dehydration.
What happens if my creatinine level is abnormal?
If your results are higher than expected, your doctor may recommend further tests, like additional bloodwork or imaging, to investigate kidney issues. If levels are low, they may check for other causes like muscle loss or liver disease. Follow-up depends on your symptoms and overall health.
Can diet affect creatinine levels?
Dietary changes alone won’t drastically alter creatinine levels, but eating a high-protein diet may temporarily increase muscle breakdown, which could slightly raise levels. Hydration status also matters—dehydration can raise creatinine, while overhydration may lower it.
Your doctor will determine how often you need this test based on your health status. People with kidney disease may need tests every few months, while others with stable conditions may only need it once a year or less.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy