: Lepirudin Induced Platelet Aggregation in Serum or Plasma by Light Transmission Aggregometry
: This test measures how strongly a person's platelets clump together when exposed to lepirudin, a direct thrombin inhibitor anticoagulant, using a light-based laboratory method. It helps assess whether lepirudin affects platelet function.
[": The test gauges platelet clumping in response to lepirudin to evaluate a possible drug effect on platelets."]
Key facts at a glance
- LOINC
- 73316-2
- Short code
- Lepirudin ind plt IgM SerPl Ql FC
- Synonyms
- Lepirudin ind plt IgM SerPl Ql FC
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
: What This Test Measures
: Platelets are small blood cells that help form clots. Light transmission aggregometry is a method that shines light through a sample and detects changes in how much light passes through as platelets clump together. This test applies that method to serum or plasma after exposure to lepirudin.
: Why Lepirudin Matters
: Lepirudin is an anticoagulant that blocks thrombin, a key protein in clotting. Because it affects clotting pathways, laboratories may study whether it also influences how platelets aggregate, which can matter when monitoring patients on this type of medication.
: How the Sample Is Handled
: A blood specimen is collected and processed to serum or plasma for testing. The laboratory then adds lepirudin and observes the platelet response using the aggregometry instrument. Results are reported based on how the sample responds compared with expected patterns.
: What the Results May Indicate
: Results can suggest whether platelets respond normally, weakly, or strongly to lepirudin under test conditions. Interpretation depends on the individual's medications, platelet count, and clinical context, so results are best reviewed with the ordering clinician.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
: This assay provides information about platelet reactivity in the presence of lepirudin, a direct thrombin inhibitor. It can support evaluation of drug-related platelet effects, but it is not a standalone diagnostic and should be interpreted alongside the patient's history, medication list, platelet count, and other coagulation studies. Abnormal findings do not by themselves confirm a bleeding or clotting disorder.
Short name
: Lepirudin Platelet Aggregation
Frequently asked questions
: Does this test diagnose a bleeding disorder?
: Do I need to stop my medications before this test?
: Is a numeric reference range included here?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy