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Serum Leucine Amino Acid Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the amino acid leucine in your blood serum. Leucine is one of the essential amino acids needed for muscle repair and protein synthesis.

Quick summary

["Leucine helps your body build muscle and maintain protein levels; abnormal results may signal metabolic or muscle-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13403-1
Short code
Leucine Amn-mCnc
Synonyms
Leucine Amn-mCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Leucine is a branched-chain amino acid (BCAA) that plays a key role in muscle metabolism and protein production. Your body uses it to repair tissues, produce energy, and support overall protein function. This test helps assess whether your leucine levels are within normal ranges for your health status.

Why Might You Need This Test?

Doctors may order this test if you have symptoms like muscle weakness, unexplained fatigue, or conditions affecting metabolism (e.g., liver disease, kidney issues, or certain genetic disorders). It can also be part of monitoring for muscle wasting or nutritional deficiencies.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if your doctor specifies. Wear loose clothing and fasten your shirt for easy access. Bring any medications or supplements you take daily to discuss with your provider.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it’s usually over quickly. The blood sample is then sent to a lab for analysis of leucine concentration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated leucine levels may indicate conditions like liver disease, kidney problems, or certain metabolic disorders. Low levels could suggest muscle breakdown, malnutrition, or disorders affecting amino acid metabolism. Your doctor will interpret results in the context of your symptoms and overall health.

Short name

Leucine Level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready to discuss the findings.
What does a normal range mean for me?
A normal range doesn’t apply universally—it depends on your health status, age, and other factors. Your doctor will compare your results to your baseline or specific medical needs to determine if further action is needed.
Can lifestyle changes affect leucine levels?
Yes, diet and exercise can influence leucine levels. High-protein diets or intense muscle activity may temporarily raise levels, while poor nutrition or muscle loss could lower them. Always discuss dietary changes with your doctor before making significant adjustments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy