Skip to content

Serum Leucine Amino Acid Profile (Qualitative Electrophoresis)

Published: August 9, 2026Updated: August 16, 2026

This test measures the qualitative presence of leucine and related amino acids in your serum using electrophoresis. It helps assess metabolic or genetic conditions affecting amino acid metabolism.

Quick summary

["This test may help diagnose conditions like inborn errors of metabolism or aminoacidopathies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45384-5
Short code
Leucine Cry #/area UrnS LPF
Synonyms
Leucine Cry #/area UrnS LPF
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-light-lpf
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates amino acids based on their electrical charge and size. This qualitative method detects abnormal levels or patterns of leucine and other amino acids that may indicate underlying metabolic issues.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like recurrent vomiting, developmental delays, or neurological concerns. It’s often used in newborn screening or when other metabolic tests suggest amino acid imbalances.

Sample Preparation

A blood sample is drawn from a vein in your arm. The serum portion is separated and sent to the lab for electrophoresis analysis. No special preparation is needed, but fasting may be required depending on clinical context.

Common Conditions Evaluated

This test can help identify conditions such as maple syrup urine disease, homocystinuria, or other aminoacidopathies where leucine and related amino acids accumulate abnormally.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Leucine Profile (Qualitative)

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result may indicate an aminoacidopathy or metabolic disorder. Your doctor will review your symptoms, medical history, and other test results to determine the next steps, which could include further genetic testing or dietary modifications.
How long will it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you once results are ready.
Can I eat or drink before this test?
Check with your doctor or lab technician for specific instructions, as fasting may be required for accurate results in some cases. Avoiding certain foods or drinks for 12–24 hours before testing can help ensure reliable outcomes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy