Leukocyte esterase in urine (qualitative)

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, pain or burning during urination, cloudy or strong-smelling urine, or fever. It can also be used as part of a general health screening or to monitor conditions like kidney disease or urinary tract infections.

How the Test Works

A small urine sample is collected, usually by urinating into a clean container. The sample is then tested for leukocyte esterase using a dipstick method. If the enzyme is present, the test strip will change color, indicating possible infection or inflammation.

What the Results Mean

A positive result (color change) suggests there may be white blood cells in your urine, which could indicate an infection or inflammation. A negative result means no enzyme was detected, but this does not rule out infection entirely. Follow-up testing or additional evaluation may be needed.

Possible Causes

Positive results can be due to urinary tract infections (UTIs), kidney infections, bladder inflammation, or other conditions causing white blood cells in urine. Negative results do not confirm the absence of infection; other tests may be required.