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Leukotriene E4 in Urine (24-Hour Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures a specific inflammatory mediator found in your urine over a full day. Leukotrienes are compounds involved in allergic reactions and inflammation.

Quick summary

["Helps assess chronic inflammation or allergic responses in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101681-5
Short code
Leukotriene E4, Rnd, Urine
Synonyms
Leukotriene E4, Rnd, Urine
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent asthma, chronic sinusitis, or other conditions linked to long-term inflammation. It could also be used to monitor treatment effectiveness in certain inflammatory or allergic conditions.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period in a special container provided by your lab. Drink enough fluids to ensure complete collection, but avoid certain medications that might interfere with results.

What the Test Measures

Leukotriene E4 is a product of arachidonic acid metabolism, released during inflammation or allergic reactions. Elevated levels may indicate ongoing inflammatory processes in your body.

How the Results Are Used

Higher-than-normal levels might suggest chronic inflammation, asthma, or other conditions affecting your respiratory or sinus health. Your provider will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Leukotriene E4 in Urine Testing

Short name

Urine Leukotriene E4 (24h)

Frequently asked questions

How long does it take to get my test results?
Results are typically available within 1–3 business days, depending on your lab’s processing schedule. Follow-up with your healthcare provider to discuss the meaning of your results.
Can I take any medications before this test?
Some medications (like NSAIDs or certain asthma treatments) may affect results. Always inform your provider or lab technician about all medications you’re taking.
What does a high or low level mean?
A high level may indicate chronic inflammation or allergic activity, while low levels suggest reduced inflammation. Your provider will explain what your specific results mean for your health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy