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Leukocyte Count with Differential (Serum/Plasma Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total number of white blood cells (WBCs) in your blood and breaks them down into specific types (neutrophils, lymphocytes, monocytes, eosinophils, and basophils). It helps assess immune function and response to infection or inflammation.

Quick summary

["Understanding your white blood cell counts can help identify infections, immune disorders, or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59294-9
Short code
Levamisole Tiss-mCnt
Synonyms
Levamisole Tiss-mCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions such as infections (like bacterial or viral infections), autoimmune diseases, blood disorders, or to check for signs of cancer. It can also be used during pregnancy, before surgeries, or to evaluate chronic illnesses like leukemia or lymphoma.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if blood is drawn from a vein (venipuncture), but this depends on your doctor’s instructions. If you’re taking certain medications, mention them to your healthcare provider.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. The blood sample is then sent to a lab, where it is analyzed to count and identify the different types of white blood cells.

What the Results Mean

Results show your total WBC count and the percentage of each type. For example, high counts may indicate infection or inflammation, while low counts could signal immune suppression or other health issues. Your doctor will interpret these results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

WBC with Differential

Frequently asked questions

What causes abnormal white blood cell counts?
Abnormal WBC counts can result from infections (bacterial, viral, or fungal), autoimmune diseases, cancers (like leukemia), or certain medications. Stress, chronic illnesses, or even allergies can also affect your immune system and lead to changes in WBC levels.
How long does it take to get my results?
Test results are typically available within 1–2 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
Most often, no special diet is required, but your doctor may advise fasting for 8–12 hours if blood is drawn from a vein. Always follow your healthcare provider’s instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy