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Levetiracetam/Creatinine Ratio, Urine — Calculated

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of levetiracetam in urine relative to urine creatinine, helping account for differences in urine concentration.

Quick summary

["This test can help assess levetiracetam exposure and whether the drug is being taken as prescribed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87765-4
Short code
levETIRAcetam/Creat Ur Cfm
Synonyms
levETIRAcetam/Creat Ur Cfm
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This is a urine test that measures levetiracetam, an antiseizure medicine, relative to creatinine, a substance produced by the muscles. The ratio helps account for how concentrated or dilute a urine sample is.

Why might I need this test?

Your clinician may use this test to monitor medication exposure, check adherence, or investigate possible side effects or changes in drug clearance. It may be especially relevant if kidney function, medication doses, or seizure control changes.

How is the test performed?

You provide a urine sample in the container specified by the laboratory. The laboratory measures levetiracetam and creatinine and calculates their ratio. Collection timing may be important and should follow your clinician's instructions.

How do I prepare for the test?

Follow any instructions about when to collect the sample, including whether a timed or first-morning collection is needed. Tell the laboratory and your clinician about medicines, supplements, and changes in kidney function that could affect the result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine levetiracetam/creatinine ratio

Frequently asked questions

Does this test show whether I took my levetiracetam as prescribed?
It can provide evidence of recent levetiracetam exposure, but it cannot by itself prove exactly when or how often the medicine was taken.
Why is creatinine included in the result?
Creatinine helps show how concentrated the urine is. Including it makes comparisons between urine samples less dependent on differences in fluid intake or dilution.
Are there other reasons my result may be unexpected?
Yes. The timing of the sample, levetiracetam dose, kidney function, fluid intake, and medicines that affect drug metabolism or elimination can all influence the result.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy