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Levetiracetam (Serum or Plasma Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of levetiracetam, a medication used to control certain types of seizures, in your blood.

Quick summary

["Knowing your levetiracetam level helps ensure your dose is effective and safe."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42249-3
Short code
levETIRAcetam Ur Ql Scn
Synonyms
levETIRAcetam Ur Ql Scn
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to check if your levetiracetam levels are within the recommended range. This helps prevent seizures from returning or causing side effects like dizziness, fatigue, or mood changes. It may also be done if you’re experiencing unusual symptoms while taking the medication.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into a vein (venipuncture) in your arm, or a blood sample may be collected from a finger. If you’re taking levetiracetam orally, your blood sample will be taken at a time that matches your usual dosing schedule.

What the Test Results Mean

Results are typically reported as the concentration of levetiracetam in your blood. Your provider will compare these results to the standard range for your age and health condition to determine if your dose needs adjustment. Very high or very low levels can indicate issues with how your body processes the medication.

Possible Side Effects and Risks

While rare, very high levetiracetam levels may cause serious side effects like confusion, difficulty breathing, or even seizures. Very low levels might mean your seizures aren’t well controlled. Your provider will monitor your results closely and adjust your dose as needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Levetiracetam Level

Frequently asked questions

What symptoms might indicate I need this test?
Your provider may recommend this test if you’re experiencing new or worsening seizure symptoms, unexplained fatigue, mood changes, or if you’re having trouble controlling your seizures with your current dose. It’s also done periodically to ensure your medication is working as intended.
How often will I need this test?
The frequency depends on your medical condition and how your body responds to the medication. Some people need tests every few weeks, while others may only need them once a month or less. Your provider will let you know the schedule.
Can I eat or drink before the test?
You can usually eat and drink normally before the test unless your provider gives specific instructions. Blood tests don’t require fasting unless they’re checking for substances like glucose or lipids, which would require different preparation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy