Levofloxacin concentration in serum/plasma (24-hour urine collection)

Why This Test Is Done

Your healthcare provider may order this test if you’re taking levofloxacin (a fluoroquinolone antibiotic) to treat or monitor an infection. It helps assess whether the medication is reaching the right levels in your body to fight bacteria effectively. This is especially important for infections in hard-to-treat areas, like urinary tract infections or certain skin or bone infections.

What to Expect Before the Test

You’ll likely need to collect all your urine for 24 hours in a special container. Drink plenty of fluids to help your kidneys pass the antibiotic through your urine. Avoid foods or supplements that might interfere with the test results. Follow your provider’s instructions carefully.

What the Results Mean

The results show the total amount of levofloxacin in your urine over 24 hours. Higher-than-expected levels may indicate the antibiotic is working well, while very low levels could mean your dose needs adjustment. Your provider will interpret these results in the context of your symptoms and medical history.

Possible Side Effects or Considerations

Levofloxacin is generally safe but can cause side effects like nausea, diarrhea, or allergic reactions in some people. Long-term use or high doses may increase risks of tendon damage or nerve problems. If you experience severe side effects, contact your provider immediately.