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Levothyroxine Absorption Panel, Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This panel measures how well your body absorbs levothyroxine, a thyroid hormone medicine, by checking hormone levels in blood at set times after a dose.

Quick summary

["It helps your care team understand whether your thyroid medicine is being absorbed properly or if absorption problems may explain poor response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90795-6
Short code
Levothyroxine absorption pnl SerPl
Synonyms
Levothyroxine absorption pnl SerPl
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Panel Measures

The panel typically checks thyroid hormone levels in serum or plasma before and at intervals after a dose of levothyroxine. It may include thyroid stimulating hormone (TSH) and free thyroxine (free T4), which help show how much hormone is circulating and how your body is responding.

Why Your Clinician Might Order It

Your clinician may order this panel if your thyroid hormone levels stay low or your symptoms do not improve despite taking levothyroxine. It can also be considered when there is concern about absorption problems in the stomach or intestines.

How the Test Is Done

Blood samples are usually collected at scheduled times around a levothyroxine dose. The exact timing and number of samples are set by the ordering laboratory or clinician, so follow their instructions carefully, including whether to take the medicine at home beforehand.

What the Results Mean

Results are interpreted as a pattern over time rather than as a single number. A rise in thyroid hormone levels after the dose suggests absorption is occurring. Your clinician will compare results with your dose, other medicines, and health history to decide if changes are needed.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Levothyroxine Absorption Test Panel

Frequently asked questions

Do I need to fast or stop my thyroid medicine before this test?
Follow the instructions from your clinician or laboratory. Fasting and medicine timing can vary, so do not stop levothyroxine unless your clinician tells you to.
Can other medicines or supplements affect the results?
Yes. Products containing calcium, iron, or certain antacids, and some other medicines, can reduce levothyroxine absorption. Tell your clinician about everything you take.
Is one blood draw enough for this panel?
No. This type of panel usually requires multiple timed blood samples to see how hormone levels change after a dose. The schedule is set by your care team.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy