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Lymphocyte Subset Analysis (Serum/Plasma) with Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and proportions of white blood cells called lymphocytes in your blood, often analyzed using an electrophoresis method to separate cell types.

Quick summary

["Understanding your lymphocyte breakdown helps doctors assess immune function and detect conditions like infections or immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59808-6
Short code
Lg Gran Lymphs Bld Ql
Synonyms
Lg Gran Lymphs Bld Ql
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to evaluate your immune system, diagnose conditions like lymphoma, chronic infections (e.g., HIV), or autoimmune diseases. It can also help monitor treatment progress for certain blood disorders.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test involves separating your blood cells to analyze lymphocyte types and proportions.

What the Results Mean

Results show the percentage or absolute count of different lymphocyte subtypes (e.g., T-cells, B-cells, natural killer cells). Abnormal results may indicate immune deficiencies, infections, or cancers.

Common Conditions Affecting Results

Low or high lymphocyte counts can signal immune disorders, chronic illnesses, or reactions to treatments. For example, low counts may suggest HIV or chemotherapy side effects, while high counts could indicate infections or overactive immune responses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lymphocyte Profile by Electrophoresis

Frequently asked questions

What questions might you have?
This test is primarily used for diagnostic and monitoring purposes, not for routine screening unless symptoms suggest immune issues. Results are interpreted by your healthcare provider in the context of your overall health.
How often should I get this test?
Frequency depends on your medical condition. Some patients need it monthly or annually, while others may only need it when symptoms or test results suggest changes in lymphocyte levels.
Can lifestyle changes affect these results?
Yes, stress, infections, or certain medications (e.g., steroids) can temporarily alter lymphocyte counts. Your doctor may adjust timing of tests based on your recent health status.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy