Skip to content

Granulocyte Lymphocyte Ratio (GLR) from Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the relative proportion of granulocytes (white blood cells like neutrophils) to lymphocytes (another type of white blood cell) in your blood.

Quick summary

["Understanding your immune cell balance can help identify infections, inflammation, or immune system conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30420-4
Short code
Lg Gran Lymphs NFr Bld
Synonyms
Lg Gran Lymphs NFr Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is the Granulocyte Lymphocyte Ratio (GLR)?

The GLR compares the number of granulocytes (a type of immune cell involved in fighting acute infections) to lymphocytes (longer-lasting immune cells). This ratio can shift depending on your health status, such as during infections, immune responses, or certain medical conditions.

Why Might You Need This Test?

Your doctor may order a GLR test to assess immune function, especially if you have symptoms like frequent infections, unexplained fevers, or signs of chronic inflammation. It can also help monitor conditions like leukemia, autoimmune diseases, or immune deficiencies.

How Is the Test Performed?

A small blood sample is drawn from a vein, typically in your arm. The blood is analyzed to count the types of white blood cells, and the GLR is calculated based on these counts.

What Does a GLR Result Mean?

Results can vary based on individual health and medical history. A high GLR might suggest an acute infection or stress response, while a low GLR could indicate chronic infection, immune suppression, or certain blood disorders. Your doctor will interpret the result in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

GLR

Frequently asked questions

What could cause a change in my GLR?
Changes in GLR can occur due to infections (like bacterial or viral), inflammation, stress, certain medications, or underlying immune disorders. For example, a high GLR may signal an acute infection, while a low GLR could point to conditions like chronic lymphocytic leukemia or immune suppression.
How soon will I get my results, and what should I do next?
Results are typically available within 24 to 48 hours, depending on your lab. Your doctor will discuss the findings with you and recommend any follow-up steps, such as additional tests or treatments based on your symptoms and medical history.
Can I eat or drink before this test?
You may eat and drink normally before the test unless your doctor instructs otherwise. No special preparation is needed, but avoid heavy meals or alcohol that could affect blood composition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy