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Platelet Count (Automated Blood Cell Differential)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of platelets in your blood, which are tiny cells that help prevent bleeding and aid in clotting.

Quick summary

["Platelets help your blood clot and prevent excessive bleeding; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48386-7
Short code
Lg Platelets/Platelet NFr Bld Auto
Synonyms
Lg Platelets/Platelet NFr Bld Auto
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
150
Ref high
400
Critical range
50 N/A – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85049
SNOMED
900000000000003003
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order a platelet count to check for bleeding disorders, clotting issues, or other conditions affecting blood cell production. It’s often done during routine blood tests or when symptoms like easy bruising, excessive bleeding, or unusual fatigue appear.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or hand to draw blood. The process takes about 5 minutes, and you may feel a brief pinch. If you’re on blood thinners, let your provider know before testing.

What the Results Mean

Platelet counts are typically reported as a range (e.g., 150,000 to 450,000 platelets per microliter of blood). Very low counts (thrombocytopenia) may increase bleeding risk, while very high counts (thrombocytosis) could raise clot formation concerns. Your provider will interpret results in relation to your symptoms and overall health.

Common Conditions Linked to Platelet Counts

Abnormal platelet counts can signal conditions like leukemia, liver disease, infections, or autoimmune disorders. Chronic conditions like kidney disease or certain medications may also affect platelet levels.

Reference range

Adult: 150-400 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Platelet counts are crucial for diagnosing bleeding disorders (e.g., hemophilia) or clotting disorders (e.g., disseminated intravascular coagulation). They help guide treatment for conditions like chemotherapy-related thrombocytopenia or platelet dysfunction from medications.

Short name

Platelet Count

Frequently asked questions

What causes a low platelet count?
Low platelet counts (thrombocytopenia) can result from bone marrow disorders (e.g., leukemia), medications (like chemotherapy or NSAIDs), autoimmune diseases (e.g., lupus), or liver/kidney problems. Infections or pregnancy may also temporarily reduce platelet levels.
What causes a high platelet count?
High platelet counts (thrombocytosis) can stem from chronic inflammation, certain cancers, or iron deficiency. Stress, infections, or blood loss may also trigger a temporary spike. Rarely, genetic conditions cause persistent elevation.
How often should I get this test?
Frequency depends on your health. Routine adults may get platelet counts as part of annual blood work, while those with bleeding disorders or clotting risks may need monitoring every few months or more often.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy