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Placental Lactogen (Human Chorionic Gonadotropin) with Triple Hormone Profile (LH, FSH, Prolactin) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures three hormones—human chorionic gonadotropin (hCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin—from a blood sample to assess pregnancy-related hormone levels and overall reproductive health.

Quick summary

["Helps diagnose or monitor conditions like early pregnancy, hormone imbalances, or fertility issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40374-1
Short code
LH 1h p Triple Bolus SerPl-aCnc
Synonyms
LH 1h p Triple Bolus SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Human chorionic gonadotropin (hCG) is a hormone produced during pregnancy that signals the body to continue producing progesterone. Elevated levels typically indicate pregnancy, though false positives can occur. LH and FSH are pituitary hormones that regulate ovulation and sperm production. Prolactin is involved in milk production and can be influenced by pregnancy, thyroid issues, or medications.

Why It’s Ordered

Your healthcare provider may recommend this test to confirm pregnancy, evaluate infertility, check for hormonal imbalances, or investigate symptoms like missed periods, irregular bleeding, or unexplained fatigue.

Common Reasons for Testing

This test is often used in early pregnancy screening, fertility evaluations, or when monitoring conditions like hyperprolactinemia (high prolactin levels). It may also be part of a broader assessment for hormonal disorders.

What to Expect Before the Test

No special preparation is needed, but avoid heavy meals 2 hours before the blood draw. Wear comfortable clothing and plan to stay for the procedure. If you’re pregnant, inform your provider before testing.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Triple Hormone Placental Test

Frequently asked questions

Why might my levels be different than expected?
Your hormone levels can vary based on factors like pregnancy status, age, medications, stress, or underlying health conditions. For example, hCG rises sharply in early pregnancy, while LH and FSH fluctuate with the menstrual cycle. Prolactin can be affected by thyroid disorders, pituitary tumors, or breastfeeding. Always discuss results with your healthcare provider.
What does a low/high result mean?
Low levels of hCG may indicate an early miscarriage or ectopic pregnancy. Low LH/FSH could signal hypogonadism (low hormone production) or advanced age-related changes. High prolactin may suggest a pituitary tumor, thyroid problems, or medications like birth control. Results should be interpreted in context with your medical history.
Can I take anything before the test?
No specific medications or supplements are restricted, but avoid alcohol or heavy meals 2 hours before the blood draw. If you’re on hormone therapy or have a medical condition, tell your provider beforehand.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy