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Plasma/Serum Creatinine with Immunoassay Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of creatinine, a waste product from muscle metabolism that your kidneys filter out of your blood. High levels may indicate kidney function issues.

Quick summary

["Creatinine helps assess how well your kidneys are working by checking waste removal efficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53145-9
Short code
LH 45M p chal SerPl-aCnc
Synonyms
LH 45M p chal SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a key marker for kidney health because it reflects how effectively your kidneys filter blood. Your kidneys normally remove creatinine from your blood, and if they’re not working well, creatinine levels can build up in your bloodstream. This test helps doctors monitor kidney function, especially in people with symptoms like fatigue, swelling, or changes in urine output.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or a blood sample collected from a finger prick. If you’re having a urine test (unlikely here), you might need to collect a sample over 24 hours. Avoiding certain medications or foods for a short time may be advised by your doctor, but this test doesn’t require strict dietary restrictions.

What the Results Mean

Results are typically compared to a reference range that varies by lab and individual factors like age, sex, and muscle mass. Higher-than-normal levels may signal kidney problems, while very low levels could indicate muscle disorders or liver disease. Your doctor will discuss your specific results in the context of your overall health.

Common Causes of Abnormal Results

Elevated creatinine levels may be caused by kidney disease, dehydration, severe muscle injury, or certain medications. Low levels might be linked to muscle wasting, liver disease, or overhydration. Conditions like diabetes or heart failure can also affect kidney function and creatinine levels.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine (Serum/Plasma)

Frequently asked questions

How often do I need this test?
The frequency depends on your health status. People with kidney disease, diabetes, or heart conditions may need this test more often, while healthy individuals might only have it as part of routine check-ups or if symptoms arise.
What if my results are out of the normal range?
If your results are abnormal, your doctor will review them with you and may recommend further tests or adjustments to your treatment plan. They’ll also consider other factors like your medical history and symptoms to determine the next steps.
Can diet or exercise affect creatinine levels?
Dietary protein intake can influence creatinine levels, but the impact is usually small. Heavy exercise or muscle breakdown may temporarily raise levels, but your doctor will account for these factors when interpreting your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy