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Luteinizing Hormone (LH)/Creatinine Ratio, 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

Measures urinary luteinizing hormone (LH) relative to creatinine in a 24-hour collection, accounting for differences in urine concentration.

Quick summary

["This test evaluates the amount of LH released into urine over 24 hours, which can help assess reproductive hormone patterns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29157-5
Short code
LH/Creat 24h Ur-Rto
Synonyms
LH/Creat 24h Ur-Rto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures luteinizing hormone (LH) and creatinine in urine collected for 24 hours. The results are expressed as an LH-to-creatinine ratio, which helps account for variations in urine concentration.

Why might I need this test?

Urinary LH measurements may be used to evaluate reproductive hormone patterns, including the timing of ovulation. A clinician may order this test when information about the menstrual cycle or fertility is needed.

How is the test performed?

You collect all urine produced during a full 24-hour period. The laboratory measures LH and creatinine and calculates their ratio.

How do I prepare for the test?

Follow the collection instructions provided by your clinician or laboratory, including the exact starting and ending times. Usually, all urine during the collection period must be included, and the container may need refrigeration if instructed.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: urine

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

LH levels rise around ovulation, so changes in this measurement may reflect the phase of the menstrual cycle. Results are interpreted alongside symptoms, other hormone tests, and fertility assessments. An unexpectedly high or low value may also be affected by an incomplete collection or other medical factors.

Short name

24-Hour Urinary LH/Creatinine Ratio

Frequently asked questions

Why is creatinine included in this test?
Creatinine is used to account for how concentrated the urine is. This allows the LH result to be more meaningfully compared between samples.
How is a 24-hour urine collection completed?
Collect every urine sample during the specified 24-hour period, beginning and ending at the times given by the laboratory. Missing urine can make the result less reliable.
Does an abnormal result mean there is a specific disorder?
No. The result must be interpreted with your menstrual-cycle timing, symptoms, medical history, and other tests; one value alone does not establish a diagnosis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy