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Luteinizing Hormone-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures luteinizing hormone relative to creatinine, helping assess hormone activity and pubertal development.

Quick summary

["This ratio can help clinicians evaluate reproductive hormone activity, particularly during puberty."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13490-8
Short code
LH/Creat Ur
Synonyms
LH/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Luteinizing hormone (LH) is a pituitary hormone involved in ovulation, testosterone production, and reproductive function. This test compares the amount of LH in urine with the amount of creatinine, a substance that reflects urine concentration.

Why might I need this test?

A urine LH-to-creatinine ratio may be used to evaluate pubertal development in children and adolescents. It may also help clinicians investigate concerns involving reproductive hormones, ovulation, or gonadal function.

How is the test performed?

A urine sample is collected and tested in the laboratory for LH and creatinine. The results are used to calculate the LH-to-creatinine ratio, which helps account for variations in urine concentration.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional, including any specified collection time. Fasting is generally not required unless your clinician says otherwise.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: urine

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine LH/creatinine ratio

Frequently asked questions

Does this test measure the same LH found in a blood test?
It measures luteinizing hormone in urine rather than blood. The result is reported relative to urine creatinine so that variations in urine concentration do not have as much effect.
Is the urine LH/creatinine ratio used for adults?
It is most often used to assess pubertal development in children and adolescents. Its usefulness for a particular adult condition depends on the clinical situation and the healthcare professional interpreting it.
What if I cannot provide a urine sample at the requested time?
Contact the ordering clinician or laboratory before collecting the sample. They can advise whether a different collection time or another type of hormone test is appropriate.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy