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L-Homoarginine/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test measuring L-homoarginine relative to creatinine. This ratio helps account for urine concentration and assists in evaluating L-homoarginine excretion.

Quick summary

["This test measures urinary L-homoarginine relative to creatinine to help evaluate its excretion and metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79587-2
Short code
L-homoarginine/Creat Ur-sRto
Synonyms
L-homoarginine/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of L-homoarginine in urine compared with the amount of creatinine. Creatinine is used as a reference because its level in urine varies with urine concentration.

Why might I need this test?

The test may be used to evaluate L-homoarginine excretion and, in some cases, investigate possible changes in arginine metabolism. It is usually interpreted along with symptoms, kidney function tests, and other laboratory results.

How is the test performed?

A urine sample is collected in a laboratory-provided container. The laboratory measures L-homoarginine and creatinine and calculates their ratio using a validated analytical method. The collection period may be a single sample or a timed collection, depending on the order.

How do I prepare for the test?

Fasting is usually not required. Follow the collection instructions exactly, including the requested collection period and timing, and tell your clinician about medicines, supplements, supplements, or unusual dietary changes that could affect the result.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: urine

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An abnormal ratio may reflect altered L-homoarginine metabolism or excretion, changes in creatinine production, hydration, or kidney function. An elevated result may prompt further evaluation for a metabolic condition, but it is not diagnostic by itself. Interpretation should be done by a clinician familiar with your symptoms and other test results.

Short name

Urinary L-homoarginine/creatinine ratio

Frequently asked questions

Why is the result reported as a ratio?
Comparing L-homoarginine with creatinine helps reduce the effect of differences in urine concentration. This makes results easier to compare across samples.
Do I need to fast before this test?
Fasting is generally not required unless your clinician specifically requests it. Follow any instructions provided for urine collection, especially if a timed collection is ordered.
Can one abnormal result diagnose a condition?
No. The result must be interpreted with your medical history, symptoms, kidney function, and other laboratory tests because hydration and several health conditions can affect it.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy