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Plasma/Serum Creatinine with eGFR Calculation (Chronic Kidney Function Assessment)

Published: August 9, 2026Updated: August 16, 2026

This test measures your creatinine level in your blood and calculates your estimated glomerular filtration rate (eGFR) to assess how well your kidneys are filtering waste products. It helps determine if you have chronic kidney disease.

Quick summary

["Your kidney function is evaluated using creatinine levels and a formula to estimate how well your kidneys are working."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27853-1
Short code
LH sp4 p chal SerPl-aCnc
Synonyms
LH sp4 p chal SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Creatinine is a waste product from muscle metabolism that your kidneys normally filter out of your blood. Higher levels can indicate reduced kidney function. The eGFR calculation combines your creatinine level with other factors (like age, sex, and race) to estimate how efficiently your kidneys are working.

Why Is This Test Important?

This test is crucial for detecting early signs of chronic kidney disease (CKD), which can progress silently. It helps doctors monitor kidney health over time and guide treatment decisions, such as adjusting medications or managing blood pressure and diabetes.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where creatinine levels are measured, and the eGFR is calculated using a standardized formula. No special preparation is needed, but fasting may be recommended in some cases.

What Are Common Results?

Results are reported as a creatinine level (in mg/dL or µmol/L) and an eGFR value (in mL/min/1.73m²). While specific reference ranges vary by lab, lower eGFR values (below 60) often signal kidney dysfunction, while higher values (above 90) generally indicate normal kidney function.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine eGFR

Frequently asked questions

How often should I get this test if I have kidney concerns?
If you have risk factors for kidney disease (such as diabetes, high blood pressure, a family history, or certain medications), your doctor may recommend this test more frequently—often every 6 to 12 months. Regular monitoring helps catch problems early and allows for timely interventions.
Can diet or lifestyle changes affect my creatinine levels?
Yes, diet and lifestyle play a role. High-protein diets or dehydration can temporarily raise creatinine levels, while staying hydrated and managing blood pressure/diabetes can help support kidney function. Always discuss dietary adjustments with your healthcare provider.
What if my eGFR is low but I feel fine?
Even if you don’t have noticeable symptoms, a low eGFR may indicate early kidney strain. Symptoms like fatigue, swelling, or frequent urination may not appear until kidney damage is more advanced. Follow-up tests and lifestyle changes can help slow progression.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy