Plasma Aldosterone-to-renin ratio (measured by immunoassay)
This test compares your body’s levels of aldosterone (a hormone that regulates blood pressure) and renin (an enzyme that helps control blood pressure and fluid balance). It helps assess whether your kidneys are properly managing these processes.
["This ratio helps diagnose conditions like primary aldosteroneism or kidney-related hypertension."]
Key facts at a glance
- LOINC
- 27854-9
- Short code
- LH sp5 p chal SerPl-aCnc
- Synonyms
- LH sp5 p chal SerPl-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 1.5
- Ref high
- 9
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms of high blood pressure (hypertension) that don’t respond to usual treatments, unexplained low potassium levels, or signs of kidney issues. It’s also used to evaluate conditions like primary aldosteroneism (Conn’s syndrome) or certain types of kidney disease.
How the Test Works
A blood sample is taken to measure both aldosterone and renin levels. The ratio helps determine if your kidneys are producing too much aldosterone relative to renin, which can indicate an overactive adrenal gland or kidney dysfunction.
What to Expect Before the Test
No special preparation is needed, but you may be asked to avoid certain medications or foods that could affect results (like salt or certain blood pressure drugs). Follow your doctor’s instructions carefully.
Possible Results and Next Steps
High ratios may suggest conditions like primary aldosteroneism, while low ratios could indicate kidney problems or other hormonal imbalances. Your doctor will discuss results and recommend further testing or treatments based on your symptoms and overall health.
Reference range
Follicular: 1.5-9.0 mIU/mLN/A
For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Aldosterone/renin ratio
Frequently asked questions
What does an abnormal aldosterone/renin ratio mean?
Do I need to fast before this test?
How long does it take to get my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy