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Plasma Aldosterone-to-renin ratio (measured by immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test compares your body’s levels of aldosterone (a hormone that regulates blood pressure) and renin (an enzyme that helps control blood pressure and fluid balance). It helps assess whether your kidneys are properly managing these processes.

Quick summary

["This ratio helps diagnose conditions like primary aldosteroneism or kidney-related hypertension."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27854-9
Short code
LH sp5 p chal SerPl-aCnc
Synonyms
LH sp5 p chal SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms of high blood pressure (hypertension) that don’t respond to usual treatments, unexplained low potassium levels, or signs of kidney issues. It’s also used to evaluate conditions like primary aldosteroneism (Conn’s syndrome) or certain types of kidney disease.

How the Test Works

A blood sample is taken to measure both aldosterone and renin levels. The ratio helps determine if your kidneys are producing too much aldosterone relative to renin, which can indicate an overactive adrenal gland or kidney dysfunction.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid certain medications or foods that could affect results (like salt or certain blood pressure drugs). Follow your doctor’s instructions carefully.

Possible Results and Next Steps

High ratios may suggest conditions like primary aldosteroneism, while low ratios could indicate kidney problems or other hormonal imbalances. Your doctor will discuss results and recommend further testing or treatments based on your symptoms and overall health.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Aldosterone/renin ratio

Frequently asked questions

What does an abnormal aldosterone/renin ratio mean?
An abnormal ratio can indicate specific health issues, such as whether your body is producing too much aldosterone (which may cause high blood pressure or low potassium) or if your kidneys aren’t working as they should. Your doctor will review your results alongside your symptoms and other tests to guide further care.
Do I need to fast before this test?
No fasting is required, but avoid certain medications (like blood pressure drugs) or foods that could influence results (like salt or specific supplements) unless instructed by your doctor.
How long does it take to get my results?
Results are typically available within a few days to a week, depending on your lab’s processing time. Your doctor will contact you once they’re ready to discuss them.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy