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Serum/plasma mass concentration of aldosterone

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands, in your blood. It helps assess how well your body regulates salt and water balance.

Quick summary

["Aldosterone helps control blood pressure and fluid balance; abnormal levels may indicate conditions like adrenal insufficiency or hypertension."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25947-3
Short code
LH sp5 p chal SerPl IRP1-aCnc
Synonyms
LH sp5 p chal SerPl IRP1-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
st-irp
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order this test if you have symptoms like high blood pressure, low blood pressure, excessive thirst, or unusual fatigue. It’s also used to diagnose conditions like primary aldosteroneism (Conn’s syndrome) or adrenal disorders.

What does the test involve?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure aldosterone levels using a sensitive mass spectrometry method.

How to prepare for the test?

No special preparation is usually needed, but your doctor may advise avoiding certain medications or dietary changes for a few days before testing.

What are the results typically used for?

Results help determine if your aldosterone levels are too high or too low, guiding treatment for conditions like hypertension, adrenal tumors, or hormonal imbalances.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Abnormally high aldosterone levels may cause hypertension, kidney problems, or low potassium. Low levels could indicate adrenal gland issues or other endocrine disorders.

Short name

Aldosterone level

Frequently asked questions

What does a high aldosterone level mean?
A high aldosterone level may suggest conditions like primary aldosteronism (Conn’s syndrome), kidney disease, or certain medications that affect blood pressure.
What does a low aldosterone level mean?
Low aldosterone levels may indicate adrenal insufficiency, Addison’s disease, or conditions affecting hormone production in the adrenal glands.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition, symptoms, and treatment plan. Follow their guidance for scheduling.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy