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Lidocaine concentration in plasma (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lidocaine, a medication used to numb areas of the body, in your blood plasma or serum.

Quick summary

["Knowing your lidocaine levels helps monitor how your body is processing this drug, especially after injections or procedures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73304-8
Short code
Lidocain ind plt IgM SerPl Ql FC
Synonyms
Lidocain ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’ve recently received a lidocaine injection (e.g., for pain relief, anesthesia, or nerve block) and need to check how your body is handling it. It can also be done if you’re experiencing unusual side effects like dizziness, confusion, or irregular heartbeat, which may signal too much lidocaine in your system.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein in your arm, similar to other routine blood tests. If you’re on other medications or have health conditions, let your provider know before the test.

How the Test Results Are Interpreted

Results are typically reported as a concentration in micrograms per milliliter (µg/mL) or milligrams per liter (mg/L). Your provider will compare these results to your clinical picture and other factors (like dose, time since administration) to guide care.

Possible Side Effects or Risks

While rare, very high lidocaine levels can cause serious side effects, such as seizures, heart rhythm problems, or low blood pressure. If you notice symptoms like nausea, vision changes, or extreme dizziness, seek medical attention immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Lidocaine Level

Frequently asked questions

What does a lidocaine level tell your doctor?
A lidocaine level helps assess whether your medication dose is appropriate for your body. For example, it can detect toxicity if levels are too high, or confirm adequate dosing if levels are within expected ranges for your situation. This is especially important for patients with liver or kidney issues, as these organs help break down lidocaine.
How often should I get this test?
The frequency depends on your treatment plan. If you’re receiving lidocaine for a specific procedure, your provider may check levels shortly after administration or if you develop symptoms. Long-term use or certain health conditions may require more frequent monitoring.
Can I stop taking lidocaine before the test?
If your provider has prescribed lidocaine for a procedure, you should not stop it unless instructed. If you’re experiencing side effects, contact your provider immediately—do not adjust the medication yourself.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy