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Total Immunoglobulin E (IgE) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to parasites.

Quick summary

["IgE helps identify allergies or immune responses that may need further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57941-7
Short code
Lime IgE/IgE total %
Synonyms
Lime IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens (substances like pollen, dust, or certain foods) or parasitic infections. While it’s normally present in small amounts, higher levels can signal allergies, asthma, or other immune conditions.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that suggest allergies. It can also help diagnose conditions like hay fever, eczema, or certain types of asthma.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab, where it’s analyzed to measure IgE levels using immunoassay methods.

What Do Results Mean?

Results are compared to standard ranges, but interpretation depends on your symptoms and medical history. Very high IgE levels may indicate allergies or immune disorders, while very low levels might suggest a weakened immune response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

How often do IgE tests affect treatment plans?
IgE test results help guide treatment for allergies or immune-related conditions. For example, high IgE may lead to allergy testing or medications like antihistamines or immunotherapy. Your doctor will discuss how the results fit into your overall care plan.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on exposure to allergens, infections, or immune responses. Repeated testing may be needed if symptoms or conditions change.
Is there anything I should avoid before the test?
No special preparations are needed. However, if you’re on allergy medications, let your doctor know before the test, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy